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Ascorbate is key in scavenging ROS and cellular processes such as electron donation to photosystem II (PSII), violaxanthin de-epoxidation, and -tocopherol reductive quenching

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Furthermore, its use for skin lightening has been associated with severe side effects

Quantification of bioluminescence signals indicated the ROS levels in the group of PEG-T ECM -NS without ROS scavenging ability was 3.41- and 2.52-fold higher than those of PEG-T ECM -NS at 24 and 72 h, respectively (Fig

It was reported that, compared with the group receiving a placebo, the group receiving VIC had a higher mortality rate